Spermine-(N,N'-bis(3-aminopropyl)-1,4-butanediamine) ≥97%, colorless solid


Synonyms: SpermineN1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine)

0215207001 02152070.5 0215207005
IC152070.5EA 69.86 USD
IC152070.5 IC15207005 IC15207001
Spermine-(N,N'-bis(3-aminopropyl)-1,4-butanediamine) ≥97%, colorless solid
Spermine (N,N'-Bis(3-aminopropyl)-1,4-butanediamine)

Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.

Caution: Research Use Only (RUO). Desiccate, store under nitrogen.

Formula: C₁₀H₂₆N₄
MW: 202.35 g/mol
Boiling Pt: 141…142 °C (0,5 mmHg)
Melting Pt: 28…30 °C (lit.)
Storage Temperature: Refrigerator
MDL Number: MFCD00008215
CAS Number: 71-44-3

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Specification Test Results

Identity Test Passes
Purity ≥97%
FTIR Conforms to Standard
pH (0.5% aq soln) 11 - 14

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