Guanosine 5'-triphosphate trisodium salt, white powder
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
GTP trisodium salt
, (((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid, trisodium salt
, (((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid trisodium salt
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Soluble in water (50 mg/mL - clear solution).
Caution: Research Use Only (RUO).
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Formula:
C₁₀H₁₃N₅Na₃O₁₄P₃ MW: 588.94 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00077781 CAS Number: 36051-31-7 |
Specification Test Results
| Identity Test | Passes |
| Purity | ≥98% |
| FTIR | Conforms to Standard |
| UV/VIS: λmax (water) | 250 - 255 nm |
| OD250/OD26 | 1.20 ± 0.0 |
| OD280/OD260 | 0.65 ± 0.0 |
| OD290/OD260 | 0.25 ± 0.0 |
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