ICNA150777

0215077750 0215077705 0215077710 0215077701
IC15077701EA 35.63 USD
IC15077701 IC15077750 76102-694 IC15077705
ICNA150777
An antineoplastic of Rhodomycin group; Antibiotic; Inhibitor of enzymes and metabolic pathways. A potent anticancer agent that has been shown to be a strong inhibitor of DNA and RNA synthesis.

  • Presentation: Powder
  • LD50 in mice 26 mg/kg in vitro.
  • Soluble in water, methanol, aqueous alcohols. Practically insoluble in chloroform, ether, benzene.

Daunorubicin hydrochloride is used in photostability , antileukemic, and drug metabolism studies.

Daunorubicin inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent. On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.

LD50 in mice 26 mg/kg in vitro.

Soluble in water, methanol, aqueous alcohols and insoluble in chloroform, ether, benzene

Caution: Protect from light
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