Actinomycin D (from Streptomyces parvulus) ~98%, crystalline powder

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
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76102-590EA 239 USD
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Actinomycin D (from Streptomyces parvulus) ~98%, crystalline powder
Actinomycin D

Actinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity.


  • Presentation: Red Crystalline Powder
  • Soluble in methanol (10 mg/mL - clear, orange solution), soluble in DMSO (50 mg/ mL-clear, orange solution), ethanol, chloroform, benzene, ethyl acetate, propylene glycol, chloroform, acetone, water + glycol mixtures.


Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumour and the sarcomas.


Actinomycin D inhibits the proliferation of cells by forming a stable complex with double-stranded DNA, inhibiting DNA-primed RNA synthesis and causing single-stranded breaks in DNA. It has been shown to be an inhibitor of the minus-strand transfer step in reverse transcriptase.


Red crystalline


Soluble in methanol (10 mg/mL - clear, orange solution), soluble in DMSO (50 mg/ mL-clear, orange solution), ethanol, chloroform, benzene, ethyl acetate, propylene glycol, chloroform, acetone, water + glycol mixtures.


Caution: Protect from light

Formula: C₆₂H₈₆N₁₂O₁₆
MW: 1255.5 g/mol
Melting Pt: 251…253 °C (lit.)
Storage Temperature: Refrigerator
MDL Number: MFCD00005033
CAS Number: 50-76-0
UN: 3462
ADR: 6.1,II
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