Dextran sulfate sodium salt, M.W. (6,000-8,000), white powder


Synonyms: Dextran sulfate sodium from DextranDextran sulphate sodium from Dextran

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IC10151850EA 639.1 USD
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Dextran sulfate sodium salt, M.W. (6,000-8,000), white powder
Dextran sulphate sodium salt

Dextran sulfate is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid. Dextran sulfate sodium (DSS) is the sodium salt which is a white to off-white powder freely soluble in water and salt solutions to form a stable, clear solution. The high purity and reproducible quality enables its application in pharmaceuticals and biotechnology industry.

Dextran Sulfate Sodium (DSS) which has proven to have versatile value in Biomedical/clinical research. DSS can be used as an anticoagulant, antiviral as well as antilipemic agent.

Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.

Solubility: Soluble in water (100 mg/ml - clear to slightly hazy yellow solution.

Caution: Research Use Only (RUO).

Formula: (C₆H₇Na₃O₁₄S₃)n
Storage Temperature: Ambient
MDL Number: MFCD00081551
CAS Number: 9011-18-1

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Specification Test Results

Identity Test Passes
pH (1% aq soln) 5.0 - 7.5
Specific Rotation +75 ° to +105 °
Loss on Drying 10%
Residue on Ignition 35 - 50%
Molecular weight Passes

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