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β-Nicotinamide Adenine Dinucleotide Phosphate Disodium Salt. ≥98%, powder

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
0210116690 0210116691 0210116680 0210116694 0210116683 0210116650
Soluble in water (50 mg/mL- clear, colorless to slight yellowish solution) or methanol; less soluble in ethanol; practically insoluble in ether and ethyl acetate.

β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of two oxidation-reduction coenzymes: nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). The nicotinamide portion of the coenzyme transfers hydrogens by alternating between oxidized quaternary nitrogen and a reduced tertiary nitrogen. NADP is an essential coenzyme for glucose-6-phosphate dehydrogenase which catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconic acid. This reaction initiates metabolism of glucose by a pathway other than the citric acid cycle. This route is known as the hexose phosphate shunt or phosphogluconate pathway. Other enzymes which utilize NADP as a coenzyme are: Alcohol dehydrogenase:NADP dependent; Aromatic ADH:NADP dependent; Ferredoxin-NADP reductase; L-Fucose dehydrogenase; Gabase; Galactose-1-phosphate uridyl transferase; Glucose dehydrogenase; L-Glutamic dehydrogenase; Glycerol dehydrogenase:NADP specific; Isocitric dehydrogenase; Malic enzymes; 5,10-Methylenetetrahydrofolate dehydrogenase; 6-Phosphogluconate dehydrogenase and Succinic semialdehyde dehydrogenase.

Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 mg 0210116680 IC10116680 Each (100mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

1 g 0210116691 IC10116691 Each (1,000mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

250 mg 0210116683 IC10116683 Each (250mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

500 mg 0210116690 IC10116690 Each (500mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

50 mg 0210116650 IC10116650 Each (50mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

5 g 0210116694 IC10116694 Each (5,000mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Enzyme Name β-Nicotinamide Adenine Dinucleotide Phosphate Disodium Salt
Purity ≥98%
Formulation White Powder
Storage Conditions Store at - 0 °C.Protect from light .Store under nitrogen.
Synonyms β-NADP; TPN; Triphosphopyridine nucleotide; NADP; Coenzyme II;β-NADH phosphate disodium salt;β-NADP-Na2
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