1,4-Dithioerythritol ≥99%, white crystalline powder


Synonyms: Cleland's ReagentDL-Dithioerythritoltrans-1,4-Dimercaptobutane-2,3-diolDTEDithioerythritol(R*,S*)-1,4-Dimercaptobutane-2,3-diolErythro-1,4-Dimercaptobutane-2,3-diol

0210059801 0210059810 0210059825
IC10059810EA 339.74 USD
IC10059810 IC10059801 IC10059825
1,4-Dithioerythritol ≥99%, white crystalline powder

Dithioerythritol is an erythro isomer of 2,3-dihydroxy-1,4-dithiolbutane, and an isomer of 1,4-dithiothreitol which is a reagent for maintaining thiols in the reduced state; prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. It also quantitatively reduces disulfides.

Dithioerythritol is used to prepare a matrix for fast-atom bombardment mass spectroscopy. It has been reported to be used in 2-D electrophoretic analysis of proteins and immunoglobulins, mitochondrial studies to block the opening of the transition pore and to study permeability transition, glial and neuronal glycine transporters have been investigated, utilized in a mass spectrometric mapping study of disulfide bonds in recombinant human interleukin-13.

Soluble in water (50 mg/ml - clear to slightly hazy, colourless solution).

Caution: Store at +4 °C, protect from light, store under nitrogen

Formula: C₄H₁₀O₂S₂
MW: 154.25 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00063750
CAS Number: 6892-68-8
EINECS: 229-998-8
UN: 3335

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Specification Test Results

Identity Test Passes
Purity ≥99%
FTIR Conforms to Reference
Melting Point 80 - 90 °C
UV/ VIS: OD283 (0.02 M aq soln) ≤0.04

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