Cycloheximide (microbial) ≥94%, white powder

Supplier: MP BIOMEDICALS (FKA ICN BIOMED

Synonyms: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide,Naramycin AActidione

0210018305 0210018325 0210018301
IC10018301EA 97.65 USD
IC10018301 75875-620 IC10018305
Cycloheximide (microbial) ≥94%, white powder
Cycloheximide

Applications
Cycloheximide is used in protein synthesis in apoptosis. It is also used in plant research to study disease resistance and as an ethylene stimulant, useful in studies involving fruit and leaf production.
Product Description
Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. It inhibits peptide synthesis in eukaryotic organisms but not in prokaryotes. Protein synthesis is blocked by the interaction of cycloheximide with the translocase enzyme. This interaction prohibits the translocation of messenger RNA on the cytosolic, 80S ribosomes without inhibiting organelle protein synthesis.
Biochem/physiol Actions
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

Formula: C₁₅H₂₃NO₄
MW: 281.35 g/mol
MDL Number: MFCD00082346
CAS Number: 66-81-9
UN: 2811
ADR: 6.1,I
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Specification Test Results

Identity Test Passes
Source Microbial
Purity (HPLC) >94%
FTIR Conforms to Standard
Melting Point 103 - 120°C

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