Acclaim™ Trinity P2 Pharmaceutical Counterion Analysis Columns, Thermo ScientificSupplier: Thermo Scientific
085432 085434 085431 085433 085435 085436
10148-550EA 1420.53 USD10148-550 10148-552 10148-554 10148-556 10148-558 10148-548
Acclaim™ Trinity P2 Pharmaceutical Counterion Analysis Columns, Thermo Scientific
The Thermo Scientific™ Acclaim™ Trinity™ P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.
- Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
- Compatibility with charged aerosol and mass spectrometry detection methods
- Retention of ionic and ionizable analytes without using ion-pairing reagents
The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology. It consists of high-purity, porous, 3 µm particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.