SETD6 also named as SET domain containing 6 is a 473 amino-acid protein, which localizes in the Nucleus. The molecular weight of SETD6 is 53kDa. SETD6 consists of 1 SET domain and belongs to the class V-like SAM-binding methyltransferase superfamily. SETD6 as a protein-lysine N-methyltransferase that specifically monomethylates at Lysine 310 of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
Western Blot: RAW 264.7 Cells, 1:200-1:2000
Type: Primary
Antigen: SETD6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse