Anti-Sodium iodide symporter Rabbit Polyclonal Antibody

Supplier: Proteintech
10094-798EA 402 USD
Anti-Sodium iodide symporter Rabbit Polyclonal Antibody
The sodium iodide symporter (Na+/I - symporter, NIS), encoded by SLC5A5, is an integral plasma membrane glycoprotein that plays an important role in iodide uptake by thyroid cells. Expression of sodium iodide symporter has also been found in extra-thyroidal tissues, including gastric mucosa, lactating mammary gland and salivary glands. Increased expression of sodium iodide symporter has been found in thyroid tissue from patients with Graves’ disease as well as papillary thyroid carcinomas. In addition, sodium iodide symporter was found to express in majority of breast cancer tissue but not in normal tissue. Sodium iodide symporter can be a promising diagnostic and therapeutic tool for thyroid cancer and breast cancer. This antibody recognizes the mature approximately 75-100 kDa protein and a partially glycosylated 50-55 kDa protein. (12588808, 9525971)

Western Blot: Mouse Testis Tissue, 1:200-1:2000; IHC: Human thyroid cancer Tissue, 1:20-1:200; FC: MCF-7 Cells, N/A

Type: Primary
Antigen: Sodium iodide symporter
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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