Anti-AGT Rabbit Polyclonal Antibody

Supplier: Proteintech
23972-1-AP-150UL
10081-912EA 402 USD
10081-912
Anti-AGT Rabbit Polyclonal Antibody
Antibodies
Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Western Blot: Human plasma Tissue, 1:500-1:5000; IF: HepG2 Cells, 1:10-1:100; IHC: Human hepatocirrhosis Tissue, 1:20-1:200

Type: Primary
Antigen: AGT
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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