Anti-RPRD1A Rabbit Polyclonal Antibody

Supplier: Proteintech
10090-930EA 402 USD
Anti-RPRD1A Rabbit Polyclonal Antibody
RPRD1A is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) and may have a role in cell cycle regulation. It contains a RAR domain that is involved in regulation of nuclear pre-mRNA, which suggests that P15RS may act as a nuclear regulation protein . It also interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Besides, RPRD1A regulates cell cycle genes and attenuates WNT signaling , and acts as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle .

Western Blot: Mouse Skeletal Muscle Tissue, 1:500-1:5000; IF: HepG2 Cells, 1:20-1:200

Type: Primary
Antigen: RPRD1A
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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