Anti-KGA/GAM/GAC Rabbit Polyclonal Antibody

Supplier: Proteintech
10089-170EA 402 USD
Anti-KGA/GAM/GAC Rabbit Polyclonal Antibody
GLS, also named as GLS1 and KIAA0838, belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-, glutamate-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells, in accordance with measurements of glutaminase activity, and had the same molecular mass of approx. 63 kDa. Ping Gao et al. (2009) determined that mitochondrial glutaminase expression (GLS, molecular mass of ~58 kDa) is increased ~10-fold in response to Myc. It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. GLS has 3 isoforms produced by alternative splicing and this antibody is specific to the 3 isoforms(KGA,GAM,GAC) of GLS.

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Kidney Tissue, 1:20-1:200; IF: HEK-293 Cells, 1:10-1:100

Type: Primary
Antigen: KGA/GAM/GAC
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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