Anti-IL6R Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-IL6R Rabbit Polyclonal Antibody

Anti-IL6R Rabbit Polyclonal Antibody

23457-1-AP-150UL

10088-852EA 537.7 USD

10088-852

Anti-IL6R Rabbit Polyclonal Antibody

Antibodies

Interleukin-6 (IL-6) is a pleiotropic cytokine produced by a variety of cells during infection, trauma, and immunological challenge . IL-6 acts via a receptor complex consisting of two distinct membrane-bound glycoproteins, an 80-kDa IL-6-binding subunit (IL-6R, CD126, gp80) and a 130-kDa signal-transducing element (gp130, CD130). After binding of IL-6 to membrane-bound IL-6R, the complex of IL-6 and IL-6R associates with gp130, thus activating the receptor . Expression of gp130 is found in almost all organs while expression of IL-6R is predominantly confined to hepatocytes and leukocyte subpopulations (monocytes, neutrophils, T cells, and B cells) . Soluble form of IL-6R has been found in human serum and urine .

Western Blot: Mouse spleen Tissue, 1:500-1:5000

Type: Primary
Antigen: IL6R
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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