Anti-XIAP Rabbit Polyclonal Antibody

Supplier: Proteintech
23453-1-AP-150UL
10097-168EA 453 USD
10097-168
Anti-XIAP Rabbit Polyclonal Antibody
Antibodies
XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells. The MW of XIAP is 45-56kd.

Western Blot:Jurkat Cells, 1:500-1:5000

Type: Primary
Antigen: XIAP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat
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