Anti-MMP12 Rabbit Polyclonal Antibody

Supplier: Proteintech
10089-670EA 402 USD
Anti-MMP12 Rabbit Polyclonal Antibody
MMP12(Matrix metalloproteinase-12) is a 54 kDa proenzyme that is processed into a 45 kDa and then a 22 kDa active form(15723202). MMP9 and MMP12 promote intimal thickening by independent cleavage of N-cadherin, which elevates vascular smooth muscle cell proliferation via beta-catenin signalling. Its overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.

Western Blot: Mouse Brain Tissue, 1:200-1:2000; IHC: Human lung cancer Tissue, 1:20-1:200

Type: Primary
Antigen: MMP12
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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