Anti-CASP1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10082-336EA 537.7 USD
Anti-CASP1 Rabbit Polyclonal Antibody
CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products. It has 5 isoforms produced by alternative splicing.

Western Blot:Jurkat Cells, 1:500-1:5000; IF:C6 Cells, 1:10-1:100

Type: Primary
Antigen: CASP1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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