C9ORF72 has a domain whith polymorphic hexanucleotide repeat (GGGGCC). The C9ORF72-hexanucleotide repeat expansions have been recently identified as genetic markers in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The C9ORF72 repeat expansions may indicate a worse prognosis in ALS. C9ORF72 has two isoforms with MW 54-60 kDa and 25-30 kDa.
Western Blot:SH-SY5Y Cells, 1:200-1:1000; IHC: Human Brain Tissue, 1:20-1:200; IF:SH-SY5Y Cells, 1:10-1:100; IP:SH-SY5Y Cells, 1:200-1:1000
Type: Primary
Antigen: C9orf72
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat