IRF-7 (interferon regulatory factor 7) is a member of the interferon regulatory transcription factor (IRF) family. IRF-7 has been shown to play a role in the transcriptional activation of virus-inducible cellular proteins, including interferon beta chain proteins. Inducible expression of IRF-7 is largely restricted to lymphoid tissue. Four transcript variants encoding distinct isoforms (A,B,C and D) have been identified for this .The active IRF7A exists as a dimer form ~80 kDa. The MW 67-70 kDa has been reported in some papers .Various posttranslational modifications of IRF7 including phosphorylation, ubiquitination, sumoylation and acetylation are identified .This antibody is a rabbit polyclonal antibody raised against the C-terminal 349 amino acid residues of human IRF7 D.
Western Blot: HEK-293 Cells, 1:200-1:2000; IHC: Human tonsillitis Tissue, 1:20-1:200
Type: Primary
Antigen: IRF7
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human