Anti-MPO Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-MPO Rabbit Polyclonal Antibody

Anti-MPO Rabbit Polyclonal Antibody

Anti-MPO Rabbit Polyclonal Antibody

Anti-MPO Rabbit Polyclonal Antibody

Anti-MPO Rabbit Polyclonal Antibody

Anti-MPO Rabbit Polyclonal Antibody

22225-1-AP-150UL

10090-374EA 402 USD

10090-374

Anti-MPO Rabbit Polyclonal Antibody

Antibodies

The MPO gene encodes myeloperoxidase, a lysosomal hemoprotein located in the azurophilic granules of polymorphonuclear (PMN) leukocytes and monocytes. In response to stimulation, MPO is activated into a transient intermediate with potent antimicrobial oxidizing abilities. The mRNA is translated into a single protein of 90 kDa, which displays enzymatic activity and undergoes proteolytic maturation into a heavy chain of 59 kDa and a light chain of 13.5 kDa; these subunits then dimerize into the mature tetramer and the mature MPO is a heterotetramer composed of two identical heavy chains and two identical light chains. The 24-kDa material had a map identical to that of 13.5 kDa subunit and represents a dimer of the 13.5 kDa subunit . Defects in MPO are the cause of myeloperoxidase deficiency (MPOD). It has 3 isoforms produced by alternative splicing. This antibody is specific to MPO.

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human Liver Tissue, 1:20-1:200

Type: Primary
Antigen: MPO
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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