SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency. This protein has 2 isoforms produced by alternative splicing.
Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human spleen Tissue, 1:20-1:200
Type: Primary
Antigen: SYK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human