Anti-SARA Rabbit Polyclonal Antibody

Supplier: Proteintech
22033-1-AP-150UL
10081-486EA 453 USD
10081-486
Anti-SARA Rabbit Polyclonal Antibody
Antibodies
ZFYVE9, also known as SARA (Smad anchor for receptor activation), is a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SARA functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization.

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Kidney Tissue, 1:20-1:200; IP: Mouse Brain Tissue, 1:500-1:5000

Type: Primary
Antigen: SARA
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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