Anti-NR3C2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10091-282EA 402 USD
Anti-NR3C2 Rabbit Polyclonal Antibody
Nuclear receptor subfamily 3 group C member 2 (NR3C2), also known as Mineralocorticoid receptor (MCR or MR), is a member of the steroid/thyroid /retinoic nuclear hormone receptor superfamily that has been shown to activate gene transcription in response to aldosterone binding. Regulation of the mineralocorticoid receptors occurs through either receptor down-regulation (negative autoregulation) or hormone-mediated upregulation (positive autoregulation). MCR association with HSP 90 appears to be required for hormone binding to MCR and subsequent MCR activation.This antibody is a rabbit polyclonal antibody, sepcifically reacts with the 107kd MCR protein.

Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human Kidney Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100

Type: Primary
Antigen: NR3C2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR