IDE(Insulin-degrading enzyme) belongs to the peptidase M16 family. It is also known as insulysin and is a 110-kD neutral metallopeptidase that can degrade a number of peptides, including insulin and beta-amyloid. The reduction of IDE expression may be a risk factor for AD, and that IDE may interact with APOE status to affect beta-amyloid metabolism. It can exsit as a homodimer and form higher oligomers. This antibody is specific to IDE.
Western Blot: HepG2 Cells, 1:500-1:5000; IHC: Human Kidney, 1:20-1:200
Type: Primary
Antigen: IDE
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat