Anti-MAP1B Rabbit Polyclonal Antibody

Supplier: Proteintech
10089-930EA 402 USD
Anti-MAP1B Rabbit Polyclonal Antibody
Microtubule-associated protein 1B (MAP1B) is a cytoskeleton protein which can promote microtubule assembly. Previous reports have suggested that this protein is closely involved in neuronal development based on its extensive expression in the developing brain and moderate in mature neurons. Gene disruption or knockout studies of the MAP1B gene led to a delayed development of the nervous system in mice. It includes the N-terminal heavy chain and a C-terminal light chain. The MAP1B heavy chain has a microtubule-stabilization effect, and contains an actin-binding site that may play a role in the crosslinking of actin and microtubules, a function that may be important in neurite elongation. Various isoforms around 300-350 kDa of MAP1B can be observed due to the differences in phosphorylation state. (10704485)

Western Blot: Mouse cerebellum Tissue, 1:200-1:2000; IHC: Mouse Brain Tissue, 1:20-1:200; FC:SH-SY5Y Cells, N/A; IF:SH-SY5Y Cells, 1:10-1:100

Type: Primary
Antigen: MAP1B
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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