Anti-TTC7A Rabbit Polyclonal Antibody

Supplier: Proteintech
10096-472EA 402 USD
Anti-TTC7A Rabbit Polyclonal Antibody
TTC7A (TPR repeat protein 7A) is expressed in enterocytes within the duodenum, ileum, and colon, and has a role in enterocyte survival and function. Mutations in the TTC7A gene can result in a spectrum of intestinal disease, including multiple intestinal atresia (MIA) and very early onset inflammatory bowel diseases (VEOIBD). Functional analysis revealed that TTC7A binds to and facilitates the transport of PI4KIIIa from the trans-Golgi to the plasma membrane, while loss of TTC7A results in dysregulation of PI4KIIIa signaling. This antibody specially recognizes endogenous TTC7A. (24417819)

Western Blot:K-562 Cells, 1:200-1:1000; IHC: Human Colon Tissue, 1:20-1:200

Type: Primary
Antigen: TTC7A
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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