Anti-TET2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10095-796EA 537.7 USD
Anti-TET2 Rabbit Polyclonal Antibody
TET2 is an enzyme which converts 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) in DNA and is important for normal myelopoiesis. TET2 mutations are frequently observed in myeloid malignancies, including myeloproliferative neoplasms. TET2 is broadly expressed in a variety of tissues. In healthy tissues, TET2 expression was shown to be elevated in hematopoietic cells with highest expression in granulocytes. Three isoforms of TET2 exists due to the alternative splicing. 220-250 kDa bands represent the full-length isoform; 130-133 kDa bands represent the nuclear isoforms of TET2. This antibody recognizes all three isoforms of TET2.

Western Blot: HL-60 Cells, 1:200-1:2000; IP: Mouse Brain Tissue, 1:200-1:2000

Type: Primary
Antigen: TET2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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