Anti-TET2 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-TET2 Rabbit Polyclonal Antibody

Anti-TET2 Rabbit Polyclonal Antibody

21207-1-AP-150UL

10095-796EA 537.7 USD

10095-796

Anti-TET2 Rabbit Polyclonal Antibody

Antibodies

TET2 is an enzyme which converts 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) in DNA and is important for normal myelopoiesis. TET2 mutations are frequently observed in myeloid malignancies, including myeloproliferative neoplasms. TET2 is broadly expressed in a variety of tissues. In healthy tissues, TET2 expression was shown to be elevated in hematopoietic cells with highest expression in granulocytes. Three isoforms of TET2 exists due to the alternative splicing. 220-250 kDa bands represent the full-length isoform; 130-133 kDa bands represent the nuclear isoforms of TET2. This antibody recognizes all three isoforms of TET2.

Western Blot: HL-60 Cells, 1:200-1:2000; IP: Mouse Brain Tissue, 1:200-1:2000

Type: Primary
Antigen: TET2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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