Anti-STIM2 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-STIM2 Rabbit Polyclonal Antibody

Anti-STIM2 Rabbit Polyclonal Antibody

Anti-STIM2 Rabbit Polyclonal Antibody

Anti-STIM2 Rabbit Polyclonal Antibody

Anti-STIM2 Rabbit Polyclonal Antibody

Anti-STIM2 Rabbit Polyclonal Antibody

21192-1-AP-150UL

10095-298EA 402 USD

10095-298

Anti-STIM2 Rabbit Polyclonal Antibody

Antibodies

STIM2, also named as KIAA1482, functions as a highly sensitive Ca2+ sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca2+-influx. Regulates basal cytosolic and endoplasmic reticulum Ca2+ concentrations. Upon mild variations of the endoplasmic reticulum Ca2+ concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca2+ release-activated Ca2+ (CRAC) channels ORAI1, ORAI2 and ORAI3. STIM2 may inhibit STIM1-mediated Ca2+ influx. STIM2 has 2 isoforms 105kd and 115kd with Differential levels of phosphorylation.

Western Blot: HEK-293 Cells, 1:1000-1:10000; IHC: Human spleen, 1:20-1:200

Type: Primary
Antigen: STIM2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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