Anti-DKK1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-876EA 402 USD
Anti-DKK1 Rabbit Polyclonal Antibody
DKK1, also named a SK and Dickkopf-1, belongs to the dickkopf family. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. SDS-PAGE and Western blot analysis demonstrated that DKK1 is expressed as a 35-kD doublet protein, which is larger than the deduced molecular mass of 26 kD. Sometime DKK1 is expressed as a 42- to 50-kD secreted protein, with little change observed after glycanase treatment.

Western Blot: Human Placenta Tissue, 1:200-1:2000; IF: HepG2 Cells, 1:10-1:100; IHC: Human gliomas Tissue, 1:20-1:200

Type: Primary
Antigen: DKK1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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