Anti-RNF170 Rabbit Polyclonal Antibody

Supplier: Proteintech

21024-1-AP-150UL

10093-798EA 402 USD

10093-798

Anti-RNF170 Rabbit Polyclonal Antibody

Antibodies

RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is speciﬁcally expressed in testis. The RING ﬁnger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.

Western Blot: Human Brain Tissue, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200

Type: Primary
Antigen: RNF170
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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