Anti-CRHR1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10084-454EA 402 USD
Anti-CRHR1 Rabbit Polyclonal Antibody
Corticotropin-releasing hormone (CRH, also known as Corticotropin-releasing factor, CRF) is a 41 amino acid peptide hormone and a key regulator of the stress response. CRH and the related urocortin peptides (UCN, UCN2 and UCN3) mediate their actions through two mammalian receptor subtypes, CRHR1 and CRHR2 . CRHR1 (also known as CRFR1) exhibits high affinity towards CRH and UCN but low affinity towards UCN2 and no affinity towards UCN3 . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Widely distributed through out the brain, CRHR1 critically controls behavioral adaptation to stress and is causally linked to emotional disorders .

Western Blot:SH-SY5Y Cells, 1:200-1:1000

Type: Primary
Antigen: CRHR1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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