Anti-CUL4B Rabbit Polyclonal Antibody

Supplier: Proteintech
10081-204EA 402 USD
Anti-CUL4B Rabbit Polyclonal Antibody
Cullin-RING ligases (CRLs) complexes participate in the regulation of diverse cellular processes, including cell cycle progression, transcription, signal transduction and development . Serving as the scaffold protein, cullins are crucial for the assembly of ligase complexes, which recognize and target various substrates for proteosomal degradation. Two cullin 4 (CUL4) proteins, CUL4A (87 kDa) and CUL4B(104 kDa), are two members in cullin family with 83% of identity. Mutations in human CUL4B are one of the major causes of X-linked mental retardation. Cul4b knockout mice demonstrated that CUL4B is indispensable for embryonic development in the mouse . Proteintech's CUL4B antibody 20882-1-AP can specifically recognize CUL4B.

Western Blot: Mouse Brain Tissue, 1:1000-1:10000; IF: Hela Cells, 1:10-1:100; IP: Mouse Brain Tissue, 1:500-1:5000

Type: Primary
Antigen: CUL4B
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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