Anti-NSUN2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10091-324EA 402 USD
Anti-NSUN2 Rabbit Polyclonal Antibody
NSUN2, also known as SAKI or Misu (Myc-induced SUN-domain-containing protein) , is a methyltransferase which catalyses (cytosine-5-)-methylation of tRNA. NSUN2 is direct target gene of c-Myc and may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is overexpressed in various cancer tissues and may be a valuable target for cancer therapy and a cancer diagnostic marker. Recently a splicing mutation in NSUN2 has been identified as the cause of a Dubowitz-like syndrome, an autosomal recessive disorder.

Western Blot:SH-SY5Y Cells, 1:500-1:5000; IHC: Human breast cancer, 1:20-1:200; IF: Hela, 1:10-1:100

Type: Primary
Antigen: NSUN2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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