Anti-TOP2B Rabbit Polyclonal Antibody

Supplier: Proteintech
10096-200EA 402 USD
Anti-TOP2B Rabbit Polyclonal Antibody
TOP2B belongs to the type II topoisomerase family. TOP2B control topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2B makes double-strand breaks. It is indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. The antibody is specific to TOP2B.

Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human cervical cancer, 1:20-1:200; IF: Hela, 1:10-1:100

Type: Primary
Antigen: TOP2B
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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