SPON2 (Spondin 2), also known as Mindin, is a member of the F-spondin family of secreted extracellular matrix proteins. This protein has been implicated in axon guidance, immune response and adhesion. SPON2 is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens . It also functions as an integrin ligand for inflammatory cell recruitment and T-cell priming . Besides, SPON2 has been reported as a prognostic biomarker for ovarian and prostate cancer .
IHC: Human Prostate Cancer Tissue, 1:20-1:200
Type: Primary
Antigen: SPON2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human