Anti-TMEM165 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-TMEM165 Rabbit Polyclonal Antibody

Anti-TMEM165 Rabbit Polyclonal Antibody

Anti-TMEM165 Rabbit Polyclonal Antibody

Anti-TMEM165 Rabbit Polyclonal Antibody

20485-1-AP-150UL

10096-088EA 462.47 USD

10096-088

Anti-TMEM165 Rabbit Polyclonal Antibody

Antibodies

Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT), a member of methyltransferase superfamily, is an enzyme involved in the normal metabolic inactivation of thiopurine drugs such as azathioprine, 6-mercaptopurine and 6-thioguanine. These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation. Defects in the TPMT gene leads to decreased methylation and decreased inactivation of 6MP leading to enhanced bone marrow toxicity which may cause myelosuppression, anemia, bleeding tendency, leukopenia and infection.

Western Blot:Jurkat Cells, 1:1000-1:10000; IF: HepG2 Cells, 1:20-1:200; IP: HeLa Cells, 1:500-1:5000

Type: Primary
Antigen: TMEM165
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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