Anti-POLR2B Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-POLR2B Rabbit Polyclonal Antibody

Anti-POLR2B Rabbit Polyclonal Antibody

Anti-POLR2B Rabbit Polyclonal Antibody

Anti-POLR2B Rabbit Polyclonal Antibody

20370-1-AP-150UL

10092-572EA 402 USD

10092-572

Anti-POLR2B Rabbit Polyclonal Antibody

Antibodies

POLR2B belongs to the RNA polymerase beta chain family. It is a DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is the second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. POLR2B proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. The antibody is specific to POLR2B.

Western Blot:A431 Cells, 1:500-1:5000; IHC: Human Brain, 1:20-1:200

Type: Primary
Antigen: POLR2B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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