LATS2, also named as KPM, belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. LATS2 is a tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity. It is a negative regulator of the androgen receptor. The antibody is specific to LATS2.
Western Blot:SGC-7901 Cells, 1:500-1:5000; IHC: Human Heart Tissue, 1:20-1:200; FC: HeLa Cells, N/A; IF: HepG2 Cells, 1:20-1:200
Type: Primary
Antigen: LATS2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human