Anti-ROBO3 Rabbit Polyclonal Antibody

Supplier: Proteintech
10093-838EA 402 USD
Anti-ROBO3 Rabbit Polyclonal Antibody
ROBO3 belongs to the immunoglobulin superfamily and ROBO family. ROBO3 is thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development it plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1. It is required for hindbrain axon midline crossing. Defects in ROBO3 are a cause of familial horizontal gaze palsy with progressive scoliosis (HGPPS). Patients show a medulla where motor and sensory projections appear uncrossed. The antibody is specific to ROBO3.

Western Blot: Mouse Brain Tissue, 1:200-1:2000; IHC: Human gliomas Tissue, 1:20-1:200

Type: Primary
Antigen: ROBO3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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