Anti-CUEDC2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-336EA 402 USD
Anti-CUEDC2 Rabbit Polyclonal Antibody
CUE domain-containing 2 (CUEDC2) is a ubiquitin-binding motif-containing protein involved in the regulation of the cell cycle, inflammation, and tumorigenesis. It is ubiquitously expressed in human tissues and organs, not only highly expressed in the normal brain, heart and testis, but also some kinds of cancers, such as breast, ovarian and kidney cancers. CUEDC2 could act as an adaptor protein to target IκB kinase (IKK) for dephosphorylation and inactivation by recruiting protein phosphatase (PP1), and thus repressed activation of the transcription factor NF-κB. Moreover, CUEDC2, is a key factor in endocrine resistance in breast cancer.

Western Blot: Human Kidney Tissue, 1:500-1:5000; IHC: Human Brain Tissue, 1:20-1:200; IF: Hela Cells, 1:10-1:100

Type: Primary
Antigen: CUEDC2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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