Anti-GNRHR Rabbit Polyclonal Antibody

Supplier: Proteintech
10087-722EA 402 USD
Anti-GNRHR Rabbit Polyclonal Antibody
GNRHR, also named as GRHR, belongs to the G-protein coupled receptor 1 family. GNRHR is a receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform2 of GNRHR may act as an inhibitor of GnRH-R signaling. Defects in GNRHR are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Defects in GNRHR are a cause of fertile eunuch syndrome. The antibody only recognizes the isoform1 of GNRHR. The predicted unmodified molecular weight of the human GNRHR is ~38 kDa, the larger band (50-60 kDa) is likely to represent a glycosylated form of GNRHR.

Western Blot: MCF7 Cells, 1:200-1:2000; IHC: Human Testis Tissue, 1:20-1:200; FC: MCF-7 Cells, N/A

Type: Primary
Antigen: GNRHR
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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