PROM1, also named as PROML1, CD133 and AC133, belongs to the prominin family. PROM1 interacts with PCDH21 and with actin filaments. CD133 is a cancer stem cell marker. Defects in PROM1 are the cause of retinitis pigmentosa type 41 (RP41)which also known as retinal degeneration autosomal recessive prominin-related. Defects in PROM1 are the cause of cone-rod dystrophy type 12 (CORD12). Defects in PROM1 are the cause of Stargardt disease type 4 (STGD4). Defects in PROM1 are the cause of retinal macular dystrophy type 2 (MCDR2). The antibody recognizes transcript variant 1,2,3 of PROM1.
Western Blot:Y79 Cells, 1:200-1:2000
Type: Primary
Antigen: CD133-1,2,3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human