Anti-CYP1A2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-504EA 537.7 USD
Anti-CYP1A2 Rabbit Polyclonal Antibody
CYP1A2, also named as CP12; P3-450 and P450(PA), belongs to the cytochrome P450 family. Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, CYP1A2 is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active of CYP1A2 is in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. It also acts in the metabolism of aflatoxin B1 and acetaminophen. CYP1A2 participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. It catalizes the reaction: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O. The antibody is specific to CYP1A2.

  • Western Blot: Mouse Liver Tissue, 1:500-1:5000; IF: Hela Cells, 1:10-1:100; FC: HeLa Cells, N/A

Type: Primary
Antigen: CYP1A2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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