Anti-SYNGAP Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-SYNGAP Rabbit Polyclonal Antibody

Anti-SYNGAP Rabbit Polyclonal Antibody

Anti-SYNGAP Rabbit Polyclonal Antibody

Anti-SYNGAP Rabbit Polyclonal Antibody

19739-1-AP-150UL

10095-510EA 537.7 USD

10095-510

Anti-SYNGAP Rabbit Polyclonal Antibody

Antibodies

SYNGAP1, also named as KIAA1938, is the major constituent of the PSD essential for postsynaptic signaling. It’s an inhibitory regulator of the Ras-cAMP pathway. SYNGAP1 is a member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. SYNGAP1 regulates AMPAR-mediated miniature excitatory postsynaptic currents. SYNGAP1 may be involved in certain forms of brain injury, leading to long-term learning and memory deficits Defects in SYNGAP1 are the cause of mental retardation autosomal dominant type 5 (MRD5).

Western Blot: Mouse Brain Tissue, 1:1000-1:10000; IF: HepG2, 1:10-1:100

Type: Primary
Antigen: SYNGAP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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