Anti-CASP3 Rabbit Polyclonal Antibody

Supplier: Proteintech
19677-1-AP-150UL
10084-088EA 402 USD
10084-088
Anti-CASP3 Rabbit Polyclonal Antibody
Antibodies
Caspase 3, also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Caspase 3 is involved in the cleavage of huntingtin. The antibody can recognize p17 and p32 of Caspase 3.

Western Blot:Jurkat Cells, 1:200-1:2000; IHC: Human Kidney Tissue, 1:20-1:200

Type: Primary
Antigen: CASP3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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