Anti-GCK Rabbit Polyclonal Antibody

Supplier: Proteintech
19666-1-AP-150UL
10087-436EA 537.7 USD
10087-436
Anti-GCK Rabbit Polyclonal Antibody
Antibodies
Glucokinase (GCK) is a structurally and functionally unique member of hexokinase family. It is expressed only in mammalian liver and pancreatic islet beta cells. Because of its unique functional characteristics, the enzyme plays an important regulatory role in glucose metabolism. The rate of glucose metabolism in liver and pancreas is a function of the activity of the enzyme. Defects in GCK are the cause of maturity-onset diabetes of the young type 2 (MODY2) and familial hyperinsulinemic hypoglycemia type 3 (HHF3). It has 3 isoforms produced by alternative splicing with the same molecular mass of 52 kDa.

Western Blot: Mouse Liver Tissue, 1:200-1:2000

Type: Primary
Antigen: GCK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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