PSMB5(Proteasome subunit beta type-5) is also named as LMPX, MB1, X and belongs to the peptidase T1B family.The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.RNAi-mediated silencing of PSMB5 expression resulted in restoration of bortezomib sensitivity in resistant cells.It has 2 isoforms produced by alternative splicing.
Western Blot:L02 Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200
Type: Primary
Antigen: PSMB5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat