Anti-MRC1 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-MRC1 Rabbit Polyclonal Antibody

Anti-MRC1 Rabbit Polyclonal Antibody

Anti-MRC1 Rabbit Polyclonal Antibody

Anti-MRC1 Rabbit Polyclonal Antibody

Anti-MRC1 Rabbit Polyclonal Antibody

Anti-MRC1 Rabbit Polyclonal Antibody

18704-1-AP-150UL

10084-296EA 453 USD

10084-296

Anti-MRC1 Rabbit Polyclonal Antibody

Antibodies

CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia. This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.

Western Blot: Human Kidney Tissue, 1:200-1:2000; IHC: Human Liver Tissue, 1:20-1:200; FC: RAW 264.7 Cells, N/A

Type: Primary
Antigen: MRC1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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