Anti-EGLN3 Rabbit Polyclonal Antibody

Supplier: Proteintech
10092-182EA 402 USD
Anti-EGLN3 Rabbit Polyclonal Antibody
EGLN3, also named as HPH-1, HIF-PH3, HPH-3 and PHD3, is a cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. It is a regulator of cardiomyocyte and neuronal apoptosis. EGLN3 can be a prognostic marker for gastric cancer.

Western Blot: HT-1080 Cells, 1:500-1:5000; IHC: Human Brain Tissue, 1:20-1:200

Type: Primary
Antigen: EGLN3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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